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    Book a same-day yellow fever vaccination near you to stay protected while traveling to high-risk regions in Africa or South America. A single dose provides long-lasting immunity.

    Yellow fever spreads through bites from infected mosquitoes.

    One vaccine dose provides immunity lasting a lifetime.

    Vaccine is required for travel to many endemic countries.

    What is yellow fever?

    Yellow fever is a viral disease transmitted primarily by mosquitoes, particularly the Aedes and Haemagogus species. According to the CDC, the virus is part of the flavivirus family and can cause a range of symptoms, from mild fever and chills to severe illness, including liver damage and bleeding. In severe cases, yellow fever can lead to high mortality rates. Vaccination is the most effective way to prevent the disease, and it is particularly important for travelers to endemic areas.

    Yellow fever occurs mainly in tropical and subtropical regions of Africa and South America. In Africa, it is prevalent in countries such as Nigeria, the Democratic Republic of the Congo, and Ghana, while in South America, it is found in areas of Brazil, Peru, and Colombia. The disease can pose a significant public health threat in these regions, particularly in areas where vaccination coverage is low, and mosquito populations are high.

    How does yellow fever spread?

    How does yellow fever spread?

    Yellow fever is primarily spread through the bite of infected mosquitoes, particularly those belonging to the Aedes and Haemagogus genera. These mosquitoes become infected when they feed on the blood of a person or an animal that has the yellow fever virus. Once infected, the mosquito can transmit the virus to other humans or animals through subsequent bites. Additionally, yellow fever can also be spread in urban areas where mosquitoes breed in close proximity to human populations. While the virus is not transmitted directly from person to person, the presence of the virus in both human and non-human primate populations plays a crucial role in maintaining its transmission cycle.

    Who should get the yellow fever shot?

    The yellow fever vaccine is recommended for individuals who are traveling to or living in areas where yellow fever is endemic, particularly in parts of Africa and South America. It is also advised for those who may be at increased risk of exposure, such as healthcare workers or laboratory personnel handling the virus. The vaccine is typically given as a single dose, which provides long-lasting immunity and is often considered effective for life in most individuals. However, some countries may require a booster dose every ten years for travelers to maintain entry requirements. It is essential for travelers to check specific vaccination requirements for their destination prior to travel.

    Who should not get the yellow fever vaccine?

    While the yellow fever vaccine is safe and effective for most people, there are certain groups who should not receive it due to a higher risk of severe side effects. You should avoid the vaccine if you:

    • Have had a severe allergic reaction to a previous yellow fever vaccine dose
    • Are allergic to any component of the vaccine (e.g., eggs, gelatin)
    • Are under 6 months of age
    • Have a weakened immune system due to disease or medication
    • Have a thymus disorder (including thymoma or thymectomy)
    • Are currently experiencing a serious illness with fever
    • Are pregnant or breastfeeding (consult your provider for risks and alternatives)

    Always speak with a healthcare provider to determine if yellow fever vaccination is safe for you

    How effective is the vaccine?

    The yellow fever vaccine is highly effective, offering protection to about 95% of people within 10 days of a single dose. For most individuals, one dose provides lifelong immunity, meaning no booster is needed. It is the most reliable way to prevent yellow fever, especially for travelers and those living in high-risk areas.

    Where to get a yellow fever vaccine

    You can get the yellow fever vaccine at designated travel clinics, some pharmacies, and certain primary care or public health offices authorized to administer it. Because not all clinics carry the vaccine, it’s important to check availability in advance. Use tools like Solv or the CDC’s travel health site to locate a nearby certified provider.

    Where to get a yellow fever vaccine

    Other common travel vaccines

    Before traveling internationally, it’s important to protect yourself against diseases that may be rare in the U.S. but common elsewhere. Vaccination can help prevent serious illness and is often required for entry into certain countries. Below are some of the most common travel vaccines and who should consider them based on destination.

    FAQs

    • Who should not get the yellow fever vaccine?

      Individuals with a severe allergy to any component of the vaccine, those with weakened immune systems, and pregnant women should consult a healthcare provider before getting the vaccine.

    • What are the side effects of the yellow fever vaccine?

      Common side effects include mild fever, headache, muscle pain, and fatigue. Rarely, serious side effects can occur, such as allergic reactions or neurological complications.

    • How can I get a yellow fever vaccine through SolvHealth?

      You can book an appointment for the yellow fever vaccine through the SolvHealth website or app by selecting a nearby clinic that offers the vaccine.

    • Can a pharmacist give a yellow fever vaccine?

      Yes, in some states, certified pharmacists are authorized to administer the yellow fever vaccine, but availability may vary by location.

    • Will my insurance cover the yellow fever vaccine?

      Coverage for the yellow fever vaccine varies by insurance plan, so it’s best to check with your insurance provider for specific details.

    • Can I travel to Africa without a yellow fever vaccine?

      Travelers to certain African countries may be required to show proof of yellow fever vaccination for entry, so it's important to check the specific requirements for your destination.

    • How long does a yellow fever vaccine last?

      The yellow fever vaccine provides long-lasting immunity, often considered effective for life, although some countries may recommend a booster every ten years.

    Dr. Rob Rohatsch, MD, is a Board-Certified Emergency Medicine physician and urgent care executive. He earned his MD from Jefferson Medical College, currently serves on multiple boards and is Solv’s Chief Medical Officer.

    How we reviewed this article

    Medically reviewed

    View this article’s sources and history, and read more about Solv’s Content Mission Statement, editorial process, and editorial team.

    Sources

    5 sources

    Solv has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references.

    • Yellow Fever Vaccine. (March 19, 2025)
    • Yellow Fever Virus. (March 19, 2025)
    • Yellow Fever. (March 19, 2025)
    • Yellow Fever. (March 19, 2025)
    • Yellow Fever Symptoms. (March 19, 2025)

    5 sources

    Solv has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references.

    • Yellow Fever Vaccine. (March 19, 2025)
    • Yellow Fever Virus. (March 19, 2025)
    • Yellow Fever. (March 19, 2025)
    • Yellow Fever. (March 19, 2025)
    • Yellow Fever Symptoms. (March 19, 2025)
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